The Denver Broncos entered Monday night's matchup with the Buffalo Bills as an underdog, albeit one with a major opportunity.
At 3-5 but carrying a two-game winning streak into Highmark Stadium, Sean Payton's squad had a chance to add its name to a crowded list of hopefuls in the AFC playoff picture, where a whopping 13 teams had between three and five losses heading into Monday night.
The Broncos delivered on that opportunity, winning 24-22 and raising hopes that the momentum can carry Denver through the second half of the season.
The Broncos snapped a seven-game losing streak on "Monday Night Football" and won their first MNF road game since Oct. 15, 2012, at the San Diego Chargers.
Here are the most important things to know from Monday night for both teams.
Buffalo Bills
The first play of the game couldn't have gone any worse for the Buffalo Bills.
After taking the ball -- going against coach Sean McDermott's typical trend of deferring to the second half -- running back James Cook fumbled on the first play after catching a pass from quarterback Josh Allen and gave the Broncos a golden opportunity. Denver seized it and went on to upset the Bills 24-22 Monday night.
The Bills came in needing a win ahead of the second-toughest remaining strength of schedule to end the season.
Instead, the game was error-filled and messy from start to finish as they tied their season high with four turnovers. Allen had one of his worst performances of the season with two interceptions (one on a drop by wide receiver Gabe Davis), one passing touchdown and one rushing touchdown. Allen finished 15-of-26 passing for 177 yards despite being pressured on a season-low 19% of his dropbacks.
Cook did redeem himself. After being benched for three drives, the second-year rusher came back and made a key play on the final Bills scoring drive, recovering his own fumble on a run that ultimately resulted in a 42-yard gain. He finished as the first Bills running back with multiple 100-yard rushing games in a season since LeSean McCoy in 2017 (four).
Biggest hole in the game plan: First-half offense. Since Week 5, the Bills have five touchdowns and eight first-half turnovers (leading the league). Against the Broncos, Buffalo's first four drives resulted in a fumble, interception, punt and punt, allowing Denver to take an early lead.
Troubling trend: Drops. The Bills had three drops on the first four drives of the game, and wide receiver Stefon Diggs added another on the first drive of the second half. Drops were a big issue for the Bills last season as they led the league with 34, but entering Monday night, Buffalo had only eight on the season.
Buy on a breakout performance: Bills defensive backups and new additions. With three defensive starters on injured reserve and two more out with injuries, this was a test for this version of the Bills' defense. Once again, the group did its job, even with the late Broncos touchdown drive, while the offense struggled. Cornerback Rasul Douglas had a fumble recovery (forced by nickel corner Taron Johnson) that led to a Bills touchdown drive, and the unit allowed only six points off four Bills turnovers
Denver Broncos
QB breakdown: Russell Wilson was far from spectacular, but he was efficient and gave the Broncos a chance to win. Wilson completed 24 of 29 passes for 192 yards and a pair of touchdowns without a turnover, also using his legs to the tune of nine carries for 30 yards. Wilson's numbers were recorded in the face of constant pressure -- he was pressured on 53% of his dropbacks Monday, his highest rate in a game since 2018. Wilson was also sacked four times by the Bills, including what could have been a costly sack to take Denver out of field goal range on its final drive.
Promising trend: After recording seven takeaways in their first seven games, the Broncos have nine in their past two outings. They had four takeaways on Monday night, including a Justin Simmons first-quarter interception that was his NFL-leading 30th pick since 2016.
Troubling trend: The mishandled point-after attempt by Broncos holder Riley Dixon could have haunted Denver's nightmares and was emblematic of struggles in the kicking game. Wil Lutz missed a PAT and might have lost the game with a missed field goal in the closing seconds ... had Buffalo not been flagged for 12 men on the field. But it was Dixon who might have breathed the biggest sigh of relief. After his miscue, Josh Allen proceeded to drive the Bills down the field for the go-ahead score, and Dixon was redeemed only by Lutz's second shot at a winning kick.
Eye-popping Next Gen stat: Courtland Sutton's second-quarter touchdown catch had a 3.2% completion probability, the lowest on any NFL touchdown pass over the past seven seasons (2017-present). The prior lowest completion probability on a passing TD also involved Russell Wilson, then with the Seahawks -- 5.3% on a TD to Tyler Lockett in Week 5 of the 2019 season vs. the Los Angeles Rams.